Production of a Polyketide Pigment by Fusarium chlamydosporum

The present study was focused to the production of secondary metabolite by fungus, F. chlamydosporum on a non-defined medium with less concentration nitrogen; organic nitrogen source being peptone and beef extract. In this context, we have been successful in extracting polyketide pigment from fungus using homogenization technique. pigments thus extracted were subjected various purification techniques via thin layer chromatography, column UV-visible spectrophotometry, fourier-transform infrared spectroscopy finally molecular determination liquid chromatography coupled tandem quadrupole mass spectrometry (LC-MS-MS). red characterized identified be fusarubin following which its cytotoxicity evaluated vitro normal lung fibroblast cell lines (MRC-5). verge researchers identifying novel compounds for applications, can major breakthrough as has investigated exhibit many pharmacological activities. Though is reported produced other Fusarium species, foremost chlamydosporum; composition culture also unique. probably correlates pathogenesis studies comment an opportunistic pathogen.